Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

A transcutaneous wire interface for small mammals using an expanded PTFE patch.

P J Schaeffer¹, D J Pierotti

¹Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ 86011, USA. pschaeff@im.wustl.edu

Journal of Neuroscience Methods

|February 19, 2002

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Chronic cold acclimation increases thermogenic capacity, non-shivering thermogenesis and muscle citrate synthase activity in both wild-type and brown adipose tissue deficient mice.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2012

Same author

Chronic cold exposure increases skeletal muscle oxidative structure and function in Monodelphis domestica, a marsupial lacking brown adipose tissue.

Physiological and biochemical zoology : PBZ·2004

Same author

Use of allometry in predicting anatomical and physiological parameters of mammals.

Laboratory animals·2002

Same author

Fiber size and myosin phenotypes of selected Rhesus hindlimb muscles after a 14-day spaceflight.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology·2001

Same author

Fiber size and myosin phenotypes of selected rhesus lower limb muscles after a 14-day spaceflight.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology·2001

Same author

The development of the ventilatory response to cold in very young rats.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2001

This study presents a surgical method for implanting a transcutaneous wire interface in small mammals using non-bioreactive ePTFE material. The technique ensures high-quality physiological signal collection for at least 7 weeks without adverse reactions.

Area of Science:

Biomedical Engineering
Surgical Techniques
Small Mammal Research

Background:

Chronic instrumentation in small mammals is crucial for physiological studies.
Existing methods for long-term implantation can lead to adverse reactions and signal degradation.
There is a need for reliable, biocompatible interfaces for sustained data acquisition.

Purpose of the Study:

To describe a surgical implantation method for a transcutaneous wire interface in small mammals.
To utilize a non-bioreactive expanded polytetrafluoroethylene (ePTFE) material for chronic instrumentation.
To facilitate successful, long-term physiological data acquisition.

Main Methods:

Surgical implantation of a transcutaneous wire interface using ePTFE material.

Related Experiment Videos

Detailed description of the implant assembly and surgical procedure.

Evaluation of signal quality during animal rest and activity.

Main Results:

High-quality electromyography (EMG) signals were acquired during rest and activity.
Signal quality was maintained for at least 7 weeks post-implantation.
No signs of infection or adverse reactions were observed.

Conclusions:

The described surgical method provides a viable approach for long-term physiological signal collection in small mammals.
The use of ePTFE material ensures biocompatibility and minimizes adverse effects.
This technique improves the reliability of chronic instrumentation for research purposes.