Towards the comprehension of genetic mechanisms controlling brain morphogenesis

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Intraventricular Transplantation of Engineered Neuronal Precursors for In Vivo Neuroarchitecture Studies
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Intraventricular Transplantation of Engineered Neuronal Precursors for In Vivo Neuroarchitecture Studies

Published on: May 11, 2019

Antonio Simeone1

  • 1MRC Centre for Developmental Neurobiology, New Hunt's House, 4th Floor, King's College London, Guy's Campus, London Bridge, London, UK. antonio.simeone@kcl.ac.uk

Trends in Neurosciences
|February 20, 2002
PubMed

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Neurulation01:30

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the anterior...