Showing a treatment is good because it is not bad: when does "noninferiority" imply effectiveness?

Aortic calcification is associated with decreased abdominal aortic aneurysm growth.

Scientific reports·2025

Multicenter CT Image-Based Anatomic Assessment of Patients with Aortoiliac Aneurysm Undergoing Endovascular Repair with Iliac Branch Devices.

Annals of vascular surgery·2024

Image-based assessment of aortoiliac aneurysm anatomical characteristics in patients from the global iliac branch study.

Langenbeck's archives of surgery·2024

Phase III randomized clinical studies to evaluate the immunogenicity, lot-to-lot consistency, and safety of ROTAVAC® liquid formulations (ROTAVAC 5C & 5D) and non-inferiority comparisons with licensed ROTAVAC® (frozen formulation) in healthy infants.

Human vaccines & immunotherapeutics·2023

Effect of Two Years of Doxycycline Treatment on Infrarenal Aortic Neck Diameter.

EJVES vascular forum·2023

Effect of Doxycycline on Progression of Arterial Calcification in the Noninvasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA(3)CT).

Annals of vascular surgery·2023

On the generation and ownership of alpha in medical studies.

Controlled clinical trials·2004

An analysis of the effect of funding source in randomized clinical trials of second generation antipsychotics for the treatment of schizophrenia.

Controlled clinical trials·2004

Symptom recording in a randomised clinical trial: paper diaries vs. electronic or telephone data capture.

Controlled clinical trials·2004

Statistical comparison of random allocation methods in cancer clinical trials.

Controlled clinical trials·2004

Analyzing bronchodilation with emphasis on disease type, age and sex.

Controlled clinical trials·2004

Geographic variability in patient characteristics, treatment and outcome in an International Trial of Magnesium in acute myocardial infarction.

Controlled clinical trials·2004

Equity-focused patient safety: reframing cultural competence, cultural humility and structural competence as determinants of patient safety.

BMJ quality & safety·2026

Intersectional analysis of patient information leaflets for neglected tropical diseases in Argentina.

Transactions of the Royal Society of Tropical Medicine and Hygiene·2026

Closing the Solidarity Gap Requires Closing the Accountability Gap for Patient-Facing AI.

Journal of medical Internet research·2026

Design and method considerations for equity-centered implementation science and practice: A PEDALs approach.

Global health research and policy·2026

The new NHS quality strategy and the debate over patient safety.

British journal of nursing (Mark Allen Publishing)·2026

A critical reflection on community engagement in health equity research: translating principles into practice, navigating barriers, and compiling transferable lessons.

International journal for equity in health·2026

Related Experiment Videos

Showing a treatment is good because it is not bad: when does "noninferiority" imply effectiveness?

Related Concept Videos

Aortic calcification is associated with decreased abdominal aortic aneurysm growth.

Multicenter CT Image-Based Anatomic Assessment of Patients with Aortoiliac Aneurysm Undergoing Endovascular Repair with Iliac Branch Devices.

Image-based assessment of aortoiliac aneurysm anatomical characteristics in patients from the global iliac branch study.

Phase III randomized clinical studies to evaluate the immunogenicity, lot-to-lot consistency, and safety of ROTAVAC® liquid formulations (ROTAVAC 5C & 5D) and non-inferiority comparisons with licensed ROTAVAC® (frozen formulation) in healthy infants.

Effect of Two Years of Doxycycline Treatment on Infrarenal Aortic Neck Diameter.

Effect of Doxycycline on Progression of Arterial Calcification in the Noninvasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA(3)CT).

On the generation and ownership of alpha in medical studies.

An analysis of the effect of funding source in randomized clinical trials of second generation antipsychotics for the treatment of schizophrenia.

Symptom recording in a randomised clinical trial: paper diaries vs. electronic or telephone data capture.

Statistical comparison of random allocation methods in cancer clinical trials.

Analyzing bronchodilation with emphasis on disease type, age and sex.

Geographic variability in patient characteristics, treatment and outcome in an International Trial of Magnesium in acute myocardial infarction.

Equity-focused patient safety: reframing cultural competence, cultural humility and structural competence as determinants of patient safety.

Intersectional analysis of patient information leaflets for neglected tropical diseases in Argentina.

Closing the Solidarity Gap Requires Closing the Accountability Gap for Patient-Facing AI.

Design and method considerations for equity-centered implementation science and practice: A PEDALs approach.

The new NHS quality strategy and the debate over patient safety.

A critical reflection on community engagement in health equity research: translating principles into practice, navigating barriers, and compiling transferable lessons.

Related Experiment Videos

Showing a treatment is good because it is not bad: when does "noninferiority" imply effectiveness?

Related Concept Videos

Related Articles