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[The ultrastructure of human and mouse cataractous lens epithelial cell apoptosis]
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|February 21, 2002
Abstract
Objective:
To observe the relation between human senile cataract, mouse congenital cataract and lens epithelial cell apoptosis.
Methods:
Transmission electron microscope was used to observe the apoptotic morphology of the lens epithelial cells in 4 cases with senile cataract and in 2 mice with congenital cataract. The comparisons were made between the cataractous and normal transparent lens epithelial cells in human being and mice.
Results:
The apoptotic cells were found in senile cataract and mouse congenital cataract lens epithelial cells, while in all control lens epithelial cells they were few.
Conclusion:
Lens epithelial cells apoptosis is related to senile cataract and mouse congenital cataract formation.