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Updated: Jul 15, 2026
10:21
In Vivo Imaging Systems (IVIS) Detection of a Neuro-Invasive Encephalitic Virus
Published on: December 2, 2012
Viral encephalitis: familiar infections and emerging pathogens
Richard J Whitley1, John W Gnann
1Department of Pediatrics, Microbiology and Medicine, University of Alabama at Birmingham, USA. R.Whitley@peds.uab.edu
Lancet (London, England)
|February 21, 2002
Summary
Advances in diagnosing and preventing viral encephalitides, particularly herpes and enteroviral infections, are improving patient outcomes. While effective treatments remain limited, research into new therapies offers hope for managing these central nervous system infections.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Viral encephalitides are serious central nervous system infections with significant morbidity and mortality.
- Understanding of their pathogenesis and natural history has advanced considerably.
Purpose of the Study:
- To review current knowledge on viral encephalitides.
- To highlight emerging viral infections and available treatment options.
Main Methods:
- Review of recent scientific literature on viral encephalitides.
- Focus on diagnostic advancements, prevention strategies, and therapeutic interventions.
Main Results:
- Polymerase Chain Reaction (PCR) has improved diagnosis of herpes and enteroviral infections.
- Vaccination is effective for Japanese encephalitis and rabies.
- Vector control is key for arboviruses.
- Acyclovir is effective for herpes simplex encephalitis; other treatments are under evaluation.
Conclusions:
- Significant progress in understanding and managing viral encephalitides.
- Vaccination and vector control are crucial prevention strategies.
- Limited but developing therapeutic options necessitate ongoing research, especially for emerging infections.
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