Immunosuppression in transplantation. A new millennium in care

Organ transplantation has grown tremendously during the last part of the 20th century. Cyclosporine, which was introduced almost 20 years ago, revolutionized transplantation as a viable treatment for end-organ failure. Successful transplantation outcomes have increased with the use of new and improved immunosuppression agents. The 21st century promises new challenges and discoveries as transplantation advances.