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Gene expression of enzymes comprising the polyol pathway in various rat tissues determined by the competitive RT-PCR

Keiko Maekawa1, Tsuyoshi Tanimoto, Satoshi Okada

  • 1Division of Biochemistry and Immunochemistry, National Institute of Health Sciences, Setagaya, Tokyo, Japan. maekawa@nihs.go.jp

Japanese Journal of Pharmacology
|February 22, 2002
PubMed

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Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...