Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Does amphotericin B lipid complex (Abelcet) affect haematological parameters erroneously?

C Beyan1, T Cetin, K Kaptan

  • 1Department of Hematology, Gülhane Military Medical Academy, Ankara, Turkey. cengizbeyan@hotmail.com

Haematologia
|February 22, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radiation dose for common pediatric computed tomography examinations and evaluation of clinical image quality in pediatric chest CT scans.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2026
Same author

A wild fish image dataset for individual re-identification and phenotyping.

Scientific data·2026
Same author

Assessment of Radiation Dose in Neurointerventional Procedures Using a Modern Digital Fluoroscopy System.

Health physics·2026
Same author

Before emergency aneurysm surgery, CTA or DSA? A single center experience.

European review for medical and pharmacological sciences·2023
Same author

Protective effect of benfotiamine on methotrexate induced gastric damage in rats.

Biotechnic & histochemistry : official publication of the Biological Stain Commission·2020
Same author

Posterior tibial slope measurement on lateral knee radiographs as a risk factor of anterior cruciate ligament injury: A cross-sectional study.

Radiography (London, England : 1995)·2019
Same journal

The use of granulocyte colony-stimulating factor in a neutropenic renal transplant recipient.

Haematologia·2003
Same journal

Heterozygous methylene tetrahydrofolate reductase mutation with mild hyperhomocysteinemia associated with deep vein thrombosis.

Haematologia·2003
Same journal

Congenital methemoglobinemia due to NADH-methemoglobin reductase deficiency in three Indian families.

Haematologia·2003
Same journal

Angiocentric lymphomatoid granulomatosis and severe hypogammaglobulinaemia.

Haematologia·2003
Same journal

Vena cava superior syndrome due to sternal plasmacytoma in the course of systemic myeloma.

Haematologia·2003
Same journal

Hepatosplenic gamma delta T-cell lymphoma with leukemic phase successfully treated with 2-chlorodeoxyadenosine.

Haematologia·2003
See all related articles

Abelcet

Area of Science:

  • Clinical Chemistry
  • Hematology

Background:

  • Abelcet (amphotericin B lipid complex) contains large particles.
  • These particles can interfere with automated blood cell counting.

Purpose of the Study:

  • To evaluate the interference of Abelcet with blood cell counters.
  • To assess hematological parameter changes during Abelcet infusion.

Main Methods:

  • In vitro study of Abelcet drug suspension on blood cell counters.
  • Ex vivo study comparing patient hematological parameters before and during Abelcet infusion.

Main Results:

  • In vitro: Significant interference with platelet counts; minimal impact on WBC, RBC, Hb.
  • Ex vivo: Statistically significant deviations in RBC counts and Hb levels; no significant difference in other parameters.

Related Experiment Videos

Conclusions:

  • Abelcet particles cause significant in vitro interference, particularly with platelet counts.
  • Ex vivo, hematological parameter deviations are minimal, aligning with Abelcet's rapid tissue accumulation and low plasma circulation.