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Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
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Screening for cancer in children with Costello syndrome
1Washington University School of Medicine, Department of Pediatrics, Division of Hematology Oncology St. Louis, Missouri 63110, USA. debaun_m@kids.wustl.edu
American Journal of Medical Genetics
|February 22, 2002
Abstract
No abstract available in PubMed .
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When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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