Related Experiment Videos
Patellar dislocation in Kabuki syndrome.
Kenji Kurosawa1, Hiroshi Kawame, Yukikatsu Ochiai
1Department of Pediatrics, Tokyo Metropolitan Kita Medical Rehabilitation Center for the Handicapped, Tokyo, Japan. kuroken@ma3.justnet.ne.jp
American Journal of Medical Genetics
|February 22, 2002
Summary
Individuals with Kabuki syndrome can experience recurrent patellar dislocation, often diagnosed in adolescence or young adulthood. Risk factors include female sex, joint laxity, and obesity, with management ranging from bracing to surgical intervention.
Area of Science:
- Orthopedics
- Genetics
- Pediatrics
Background:
- Kabuki syndrome is a rare genetic disorder with diverse clinical manifestations.
- Recurrent patellar dislocation is a potential orthopedic complication that can affect quality of life.
Observation:
- This study details four cases of Kabuki syndrome patients experiencing recurrent patellar dislocation.
- Diagnosis ages for patellar dislocation ranged from 11 to 23 years.
Findings:
- Key risk factors for patellar dislocation in Kabuki syndrome include female sex, adolescence/young adulthood, joint laxity, and obesity.
- Management strategies involved surgical intervention (excision and tibial tuberosity transfer) and conservative measures (patellar bracing).
Implications:
- Early identification of risk factors can guide proactive orthopedic management in Kabuki syndrome patients.
- Understanding these associations may improve patient outcomes and reduce long-term morbidity associated with patellar instability.