Co-operative response of oligomeric protein receptors coupled to non-co-operative ligand binding

Framework for developing a national surgical, obstetric and anaesthesia plan.

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Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.

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Targeting melanoma with NT157 by blocking Stat3 and IGF1R signaling.

Oncogene·2015

Pharmacological inhibition of PAR2 with the pepducin P2pal-18S protects mice against acute experimental biliary pancreatitis.

American journal of physiology. Gastrointestinal and liver physiology·2013

Status of p53 in human cancer cells does not predict efficacy of CHK1 kinase inhibitors combined with chemotherapeutic agents.

Oncogene·2010

G-CSF control of neutrophils dynamics in the blood.

Bulletin of mathematical biology·2007

HuKSA: A Machine-Learning-Based Framework for Predicting Human Kinome Selectivity and Polypharmacology.

Journal of molecular biology·2026

piRTarBase2: an updated C. elegans piRNA binding site database with extensive evidence for piRNA targeting events.

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Structural basis for HKU5‑CoV main protease inhibition by the clinical antivirals nirmatrelvir and ensitrelvir.

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Two heads are better than one: Single stranded DNA translocation of UvrD-family dimers vs. monomers.

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Missense3D: leveraging protein structures, including AlphaFold models, to understand the effect of missense variants.

Journal of molecular biology·2026

HandMol at MolecularWebXR.org: Immersive, Multiuser Visualization and Interactive Modeling with Natural Interactions, on the Web Across a Wide Range of Devices.

Journal of molecular biology·2026

β-Hairpin Fold Peptide Brush Polymers.

bioRxiv : the preprint server for biology·2026

The taste of cysteine cathepsins: analyzing specificity, aiming for function.

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Biochemistry of protozoan Metacaspases: Structure, processing, and inhibition.

Biochemical pharmacology·2026

Solid-Phase Synthesis of Enteropeptin A Analogues.

Organic letters·2026

Phenolic Metabolites as Therapeutics for Chronic Diseases: One Researcher's PAINS Is Another's Translatable Polypharmacology.

Journal of natural products·2026

Curvulinic Acid-Clavatol Hybrids and Curvulinic Acid Dimers with Anti-Inflammatory Activity from Penicillium sp. KYS-21.

Journal of natural products·2026

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Co-operative response of oligomeric protein receptors coupled to non-co-operative ligand binding

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Framework for developing a national surgical, obstetric and anaesthesia plan.

Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.

Targeting melanoma with NT157 by blocking Stat3 and IGF1R signaling.

Pharmacological inhibition of PAR2 with the pepducin P2pal-18S protects mice against acute experimental biliary pancreatitis.

Status of p53 in human cancer cells does not predict efficacy of CHK1 kinase inhibitors combined with chemotherapeutic agents.

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