Related Experiment Video
Updated: Oct 2, 2026

Quantifying the Antifungal Activity of Peptides Against Candida albicans
Published on: January 13, 2023
Antifungal steroidal glycosides from the patagonian starfish anasteriasminuta: structure-activity correlations
Hugo D Chludil1, Alicia M Seldes, Marta S Maier
1Departamento de Química, Facultad de Ciencias Naturales, Universidad Nacional de la Patagonia, San Juan Bosco, Chubut, Argentina.
Abstract:
Two new sulfated steroidal hexaglycosides, anasterosides A (2) and B (3), along with the known versicoside A (1) have been isolated from the Patagonian starfish Anasterias minuta. Their structures have been elucidated by spectroscopic analysis (NMR and FABMS) and chemical transformations. Compounds 1 and 2 and the synthetic pentaglycoside 1b derived from versicoside A showed antifungal activity against the plant pathogenic fungus Cladosporium cucumerinum. Desulfation of hexaglycoside 1 rendered a totally inactive saponin.
Related Concept Videos
Antifungal Agents
Anthelminthic Agents
Antiprotozoal Agents
Adrenergic Agonists: Chemistry and Structure-Activity Relationship
Aromatic ring substitutions: Substituting the aromatic ring with –OH groups at positions 3 and 4 yields catecholamines (e.g., epinephrine), which have a high affinity for adrenoceptors. Hydrogen bonding between –OH groups and receptors enhances adrenergic activity.
Separation of the aromatic...
Inhibitors of Bacterial Protein Synthesis
Cholinergic Antagonists: Chemistry and Structure-Activity Relationship

