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Related Experiment Videos

Optic neuritis in Asian children.

Jeon-Min Hwang1, Yong Jae Lee, Mee Kum Kim

  • 1Department of Ophthalmology Seoul Municipal Boramae Hospital, College of Medicine, Seoul National University, Korea.

Journal of Pediatric Ophthalmology and Strabismus
|February 28, 2002
PubMed
Summary
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Pediatric optic neuritis in Korean children often presents bilaterally with good visual prognosis, particularly with intravenous steroid treatment. Multiple sclerosis development is rare in this population.

Area of Science:

  • Ophthalmology
  • Neurology
  • Pediatrics

Background:

  • Optic neuritis is an inflammatory condition affecting the optic nerve.
  • Understanding its clinical spectrum in pediatric populations is crucial for diagnosis and management.

Purpose of the Study:

  • To investigate the clinical characteristics and outcomes of pediatric optic neuritis in Korean children.
  • To assess factors influencing visual recovery and the risk of developing multiple sclerosis.

Main Methods:

  • Retrospective analysis of 23 Korean children diagnosed with optic neuritis before age 16.
  • Review of initial visual loss, visual recovery, MRI findings, and associated diseases.
  • Evaluation of treatment outcomes, specifically intravenous steroid therapy.

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Main Results:

  • Bilateral involvement occurred in 87% of cases, with disc swelling in 51%.
  • A preceding febrile illness was reported in 39% of patients.
  • 79% achieved final vision of ≥20/40, with significantly better outcomes in those receiving intravenous steroids (96% vs. 56%).
  • Multiple sclerosis developed in only one patient (4%).

Conclusions:

  • Pediatric optic neuritis in Korean children typically presents bilaterally with papillitis.
  • Visual prognosis is generally favorable, enhanced by intravenous steroid treatment.
  • The incidence of multiple sclerosis following optic neuritis in this demographic appears low.