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Solid phase synthesis of structurally diverse tetra substituted pyrimidines for potential use in combinatorial
1Medicinal Chemistry Division, Central Drug Research Institute, Lucknow-226001, U.P., Lucknow, India. Premsc58@hotmail.com
Combinatorial Chemistry & High Throughput Screening
|February 28, 2002
Abstract:
A new pyrimidine based scaffold has been identified for generation of combinatorial libraries using solid phase technique. The utility of the scaffolds was demonstrated by synthesizing small libraries of 12 substituted pyrimidines (4a-4l).