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Updated: Oct 2, 2026

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System
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Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System

Published on: September 20, 2018

Infantile perianal protrusion: 13 new cases

Annalisa Patrizi1, Beatrice Raone, Iria Neri

  • 1Department of Clinical and Experimental Medicine, Division of Dermatology, University of Bologna, Bologna, Italy. patrizi@med.unibo.it

Pediatric Dermatology
|February 28, 2002
PubMed

Insights

Infantile perianal protrusion in girls may be linked to lichen sclerosus et atrophicus (LS&A). This condition, affecting children aged 4 months to 5 years, did not show spontaneous reduction in the study group.

Area of Science:

  • Pediatric Dermatology
  • Pediatric Surgery
  • Gynecology

Background:

  • Infantile perianal protrusion is a rare condition affecting young girls.
  • Associated conditions like constipation and anal fissures are common.
  • Lichen sclerosus et atrophicus (LS&A) is a chronic inflammatory skin condition.

Purpose of the Study:

  • To describe the clinical presentation and associations of infantile perianal protrusion in a cohort of young girls.
  • To investigate the potential link between infantile perianal protrusion and lichen sclerosus et atrophicus (LS&A).

Main Methods:

  • Retrospective case series of 13 girls diagnosed with infantile perianal protrusion.
  • Clinical data including medical history, physical examination findings, and follow-up were reviewed.
  • Histopathological examination of biopsy specimens was performed in select cases.

Main Results:

  • Thirteen girls aged 4 months to 5 years were identified.
  • Protrusions were located anteriorly (n=8) or posteriorly (n=3) to the anus.
  • Constipation (n=6) and anal fissures (n=3) were noted comorbidities.
  • One patient with recurrent anogenital erythema showed LS&A on biopsy.
  • Two additional patients presented with clinical signs of genital LS&A.
  • No spontaneous reduction of infantile perianal protrusion was observed during follow-up.

Conclusions:

  • Infantile perianal protrusion may be associated with lichen sclerosus et atrophicus (LS&A) in girls.
  • Further investigation is warranted to understand the pathophysiology and management of this association.
  • Persistent infantile perianal protrusion necessitates thorough evaluation for underlying conditions like LS&A.

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