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Staged endoscopic operation for large pituitary adenomas
Takayuki Nakagawa1, Masahiro Asada, Tadayoshi Tadashima
1Department of Otolaryngology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. tnakagawa@hs.m.kyoto-u.ac.jp
The Journal of Laryngology and Otology
|February 28, 2002
Summary
Endoscopic transnasal pituitary surgery offers a panoramic view and facilitates reoperation. A staged approach for large pituitary adenomas proved safe and effective, enabling complete tumor removal with minimal complications.
Area of Science:
- Neurosurgery
- Endocrinology
Background:
- Endoscopic transnasal pituitary surgery provides enhanced visualization and access.
- Large pituitary adenomas extending suprasellarly pose surgical challenges.
Purpose of the Study:
- To evaluate the safety and efficacy of a planned staged endoscopic transnasal approach for large pituitary adenomas.
Main Methods:
- Two-stage endoscopic transnasal trans-sphenoidal surgery via both nostrils.
- Initial resection of intrasellar tumor, leaving capsule intact.
- Second-stage resection of residual tumor after descent.
Main Results:
- Successful resection of large pituitary adenomas in two cases.
- Residual tumor descended into the sellar floor for second-stage removal.
- No peri-operative complications reported.
Conclusions:
- A staged endoscopic transnasal approach is a safe and efficient method for resecting large pituitary tumors.
- This technique minimizes peri-operative injury and achieves complete tumor removal.