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[Study on the application of random amplified polymorphic DNA in Yersinia pestis genotyping]
1Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing 102206, China.
Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|February 28, 2002
Abstract
Objective:
To study the type of 103 Y. pestis strains that isolated from different plague foci and different ecological types.
Method:
Random amplified polymorphic DNA (RAPD) was used.
Results:
Y. pestis were divided into two RAPD types: most strains that isolated from elsewhere in the country belonged to RAPD-1 type, while most strains that isolated from Qinghai province were RAPD-2 type.
Conclusion:
The genome structures of different ecotype Y. pestis were different providing the foundation of further research and prevention of plague.