[Risk factors of type 2 diabetes in Shenzhen]

The study was designed to investigate the risk factors of Type 2 diabetes in the new city Shenzhen.

A representative sample of 8,182 adults aged over 20 to 75 years old were randomly selected in the residents of Shenzhen, China in 1997. Type 2 diabetes was diagnosed according to the WHO criteria. Questionnaire survey, anthropometric measurement and blood analysis were carried out, and logistic regression analysis was used to study the risk factors.

The results showed that the prevalence of type 2 diabetes in subjects with high total cholesterol were 4.9 times of those with lower TC value. Subjects with high triglyceride had a prevalence 5.7 times of those who had lower TG. Those HDL-ch had a prevalence 68.7% higher than those with normal HDL-ch value; on the other hand, those HDL-ch > 1.91 mmol/L were 44.6% lower in the prevalence than those with normal HDL-ch. The prevalence of type 2 diabetes in subjects with BMI >or= 25 were 2.6 times of those with BMI < 25. Subject with hypertension (>or= 140/90 mm Hg) had a prevalence 3.8 times of those with normal blood pressure. Subjects with family history of type II diabetes had a prevalence 2.0 times of no family history, and women who had delivered babies over 4 kg had a prevalence 1.9 times of those who had babies less than 4 kg. Subjects with waist/hip ratio (WHR) >or= 1.0 had a prevalence 5.1 times of those with WHR < 1.0. The prevalence of type 2 Diabetes was higher with increasing amount of cigarette smoking and the duration (in years) of smoking or increasing drinking (alcohol) and the duration (in years) of drinking.

The blood glucose level was found to be positively correlated with TC or TG, and negatively correlated with HDL-ch. This study demonstrated again that TC, TG, HDL-ch, obesity, hypertension, family history of type 2 diabetes and in women, delivery of babies over 4 kg and age were risk factors of type 2 diabetes.