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Reactivation of herpes simplex virus keratitis after initiating bimatoprost treatment for glaucoma
Debra M Kroll1, Joel S Schuman
1New England Eye Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
Purpose:
To report a case of herpes simplex virus reactivation after starting bimatoprost treatment for glaucoma.
Design:
Interventional case report.
Methods:
A 66-year-old woman had a herpes simplex keratouveitis reactivation that occurred within 1 month after starting bimatoprost. The herpes simplex had been inactive for more than 10 years.
Results:
Bimatoprost and prednisolone acetate 0.12% were discontinued; oral acyclovir, ofloxacin, and betaxolol 0.25% were initiated. Two weeks later, prednisolone acetate 1% was added. The reactivation resolved, and 1 month later, the best corrected visual acuity improved to 20/40.
Conclusion:
Caution should be used in prescribing bimatoprost for patients with a history of herpes simplex virus keratitis.