Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recent developments in contraceptive implants at the Population Council.

Irving Sivin1, Alfred Moo-Young

  • 1Population Council, Center for Biomedical Research, New York, NY, USA. sivin@popcbr.rockefeller.edu

Contraception
|February 28, 2002
PubMed
Summary

Developing new contraceptive implants is a lengthy, multi-year process involving extensive research and trials. The Population Council is advancing new levonorgestrel and Nestorone implants for extended use, demonstrating progress in long-acting reversible contraception.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Daniel R. Mishell, Jr, MD, and the journal Contraception.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2012
Same author

Seven billion people today, many more tomorrow--how we got here and what we expect and wish.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2012
Same author

Effects of a novel estrogen-free, progesterone receptor modulator contraceptive vaginal ring on inhibition of ovulation, bleeding patterns and endometrium in normal women.

Contraception·2011
Same author

Severity of infection following the introduction of new infection control measures for medical abortion.

Contraception·2011
Same author

State-of-the-art of non-hormonal methods of contraception: I. Mechanical barrier contraception.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2010
Same author

State-of-the-art of non-hormonal methods of contraception: III. Intrauterine devices.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2010

Area of Science:

  • Reproductive Health
  • Pharmaceutical Development
  • Clinical Trials

Background:

  • Contraceptive implant development is a complex, multi-decade process requiring extensive collaboration.
  • Established methods like Jadelle and Norplant are undergoing evaluations for extended usage periods.
  • New synthetic chemical entities necessitate even longer development timelines, often spanning two decades.

Purpose of the Study:

  • To present the status and rationale for developing a novel Nestorone-releasing single implant.
  • To highlight the Population Council's recent advancements in long-acting reversible contraception (LARC).
  • To discuss the extended use potential for existing levonorgestrel implants.

Main Methods:

  • Review of developmental processes for contraceptive implants, including laboratory work and clinical trials (Phase II and III).

Related Experiment Videos

  • Analysis of regulatory filings for extended use of Jadelle (5 years) and Norplant (7 years).
  • Description of studies on a new Nestorone-releasing implant for 2-year use.

    • Main Results:

    • The Population Council has completed development work on two levonorgestrel-releasing implants, supporting extended use.
    • Regulatory filings are in progress for Jadelle (5 years) and Norplant (7 years).
    • A new Nestorone-releasing implant for 2-year use is under study.

    Conclusions:

    • Contraceptive implant development is a long-term endeavor, often exceeding a decade.
    • The Population Council is actively contributing to the advancement of LARC technologies.
    • Newer implant formulations, like Nestorone, aim to provide shorter-term reversible contraception options.