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Post-thrombotic syndrome.

C Barnes1, F Newall, P Monagle

  • 1Royal Children's Hospital, Melbourne, Australia.

Archives of Disease in Childhood
|February 28, 2002
PubMed
Summary
This summary is machine-generated.

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Post-thrombotic syndrome (PTS) can affect children after deep venous thrombosis (DVT), often linked to central venous lines. Early recognition is crucial for managing this disabling condition in pediatric patients.

Area of Science:

  • Pediatric Medicine
  • Vascular Medicine
  • Clinical Case Studies

Background:

  • Post-thrombotic syndrome (PTS) is a recognized complication of deep venous thrombosis (DVT) in adults.
  • PTS has recently been identified as a potential complication in pediatric patients.
  • Central venous lines (CVLs) are increasingly used in children, posing a risk for DVT and subsequent PTS.

Observation:

  • Three pediatric cases of symptomatic PTS following CVL use are presented.
  • In two cases, acute thrombosis symptoms were absent, highlighting a subtle onset.
  • Clinical presentation includes pain, swelling, and brawny induration, similar to adult PTS.

Findings:

  • Literature review indicates an estimated 7-12% incidence of PTS in children post-DVT.

Related Experiment Videos

  • PTS is confirmed as a significant complication of DVT in the pediatric population.
  • The long-term effects of PTS on growing limbs remain unknown.

    • Implications:

    • Paediatricians must be vigilant for PTS in at-risk children, including those with malignancy, congenital heart disease, or prior CVLs.
    • Awareness is critical even when acute DVT is not documented.
    • Early identification and management are essential to mitigate the disabling effects of PTS in children.