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Exacerbation of Avellino corneal dystrophy after laser in situ keratomileusis
Xiu Hua Wan1, Hyun Chae Lee, R Doyle Stulting
1Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Brain Korea 21 Project for Med Science, CPO Box 8044, Seoul 120-752, Korea.
Purpose:
To report a case of Avellino corneal dystrophy that increased in severity 1 year after uncomplicated laser in situ keratomileusis (LASIK) for myopia.
Methods:
Avellino dystrophy was confirmed by polymerase chain reaction sequencing of DNA from the patient and her parents.
Results:
Best spectacle-corrected visual acuity decreased from 20/20 to 20/30 12 to 20 months after LASIK owing to opacities that appeared centrally in the corneal stroma and the LASIK flap and remaining posterior stroma interface.
Conclusions:
LASIK is contraindicated in patients with Avellino corneal dystrophy because vision may be reduced by corneal opacities that appear in the interface of the flap and remaining posterior stroma postoperatively.
