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Postkeratoplasty endophthalmitis by Alcaligenes faecalis: a case report
D Sudarshan Khokhar1, Harinder Singh Sethi, Harsh Kumar
1Cornea Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India. skhokhar38@hotmail.com
Cornea
|February 28, 2002
Summary
A rare case of postkeratoplasty endophthalmitis caused by Alcaligenes faecalis, a gram-negative rod, was successfully treated with antibiotics. This finding highlights the importance of donor tissue screening in preventing such infections.
Area of Science:
- Ophthalmology
- Microbiology
Background:
- Postkeratoplasty endophthalmitis is a serious complication following corneal transplantation.
- Alcaligenes faecalis is an opportunistic gram-negative bacterium rarely implicated in ocular infections.
Observation:
- A case of endophthalmitis occurred after corneal transplant.
- The causative organism, Alcaligenes faecalis, was identified and found to be resistant to gentamicin.
- The infection was traced back to contaminated donor corneal tissue.
Findings:
- This is the first reported case of postkeratoplasty endophthalmitis caused by Alcaligenes faecalis.
- Aggressive treatment with topical, systemic, and intravitreal antibiotics led to complete resolution of the endophthalmitis within two weeks.
Implications:
- Donor tissue screening for microbial contamination is crucial to prevent postkeratoplasty infections.
- Early diagnosis and prompt, appropriate antibiotic therapy are essential for managing Alcaligenes faecalis endophthalmitis.
- This case expands the spectrum of pathogens causing endophthalmitis after corneal transplantation.