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Related Experiment Videos

Keratitis caused by Verticillium species.

Jae-Yong Shin1, Hyo-Myung Kim, Jong-Wook Hong

  • 1Department of Ophthalmology, Korea University Hospital, Korea University Medical College, Seoul, Korea.

Cornea
|February 28, 2002
PubMed
Summary

This case report details a rare fungal keratitis caused by Verticillium species, highlighting the importance of considering unusual fungal infections in persistent stromal keratitis.

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Area of Science:

  • Ophthalmology
  • Medical Mycology

Background:

  • Fungal keratitis is an infection of the cornea.
  • Stromal keratitis can be challenging to diagnose and treat.

Observation:

  • A 50-year-old man presented with symptoms suggestive of herpetic keratitis.
  • Initial treatment with antiviral medication failed, and the condition worsened.
  • Examination revealed feathery stromal infiltrates and epithelial ulceration.

Findings:

  • Corneal scrapings confirmed fungal filaments, identified as Verticillium species.
  • Treatment with topical amphotericin B and systemic fluconazole led to clinical improvement.
  • This represents a rare instance of fungal keratitis caused by this specific genus.

Implications:

Related Experiment Videos

  • Verticillium species should be considered in the differential diagnosis of refractory stromal keratitis.
  • Prompt identification and appropriate antifungal therapy are crucial for managing rare fungal corneal infections.