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Related Experiment Videos

Prosthetic replacement of the aortic arch.

R B Griepp, E B Stinson, J F Hollingsworth

    The Journal of Thoracic and Cardiovascular Surgery
    |December 1, 1975
    PubMed
    Summary

    Aortic arch replacement using total body hypothermia and circulatory arrest is a viable surgical option. This technique offers an acceptable mortality rate for patients with aortic arch aneurysms.

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    Area of Science:

    • Cardiovascular Surgery
    • Thoracic Surgery
    • Vascular Surgery

    Background:

    • Aortic arch aneurysms pose significant life-threatening risks.
    • Surgical repair of the aortic arch presents complex challenges due to its critical location and vascular supply.

    Purpose of the Study:

    • To evaluate the safety and efficacy of aortic arch replacement using total body hypothermia and circulatory arrest.
    • To assess the outcomes in patients undergoing aortic arch prosthesis implantation.

    Main Methods:

    • Four patients with aortic arch aneurysms (dissecting or arteriosclerotic) underwent aortic arch replacement.
    • A combination of surface cooling and cardiopulmonary bypass induced total body hypothermia.
    • Arch replacement was performed during total circulatory arrest, followed by rewarming and cardiac resuscitation.

    Main Results:

    • The average duration of cerebral ischemia was 43 minutes and myocardial ischemia was 74 minutes.
    • The average lowest esophageal and rectal temperatures reached were 14°C and 18°C, respectively.
    • Three out of four patients survived and were well at 4-13 months post-surgery; one patient died from pulmonary insufficiency.

    Conclusions:

    • Total body hypothermia and circulatory arrest enable aortic arch replacement with an acceptable mortality rate.
    • This surgical approach can be offered to patients with life-threatening aortic arch aneurysms.

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