Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anticonvulsant-induced lymphoma.

M P Fried, Y Sunwoo

    The Laryngoscope
    |October 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Diphenylhydantoin (Dilantin) can cause cervical adenopathy and vocal cord paralysis, mimicking lymphoma. Long-term follow-up is crucial for patients on hydantoin therapy due to increased lymphoma risk.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Identifying and reducing errors with surgical simulation.

    Quality & safety in health care·2004
    Same author

    Phase I/II trial of outpatient docetaxel, cisplatin, 5-fluorouracil, leucovorin (opTPFL) as induction for squamous cell carcinoma of the head and neck (SCCHN).

    American journal of clinical oncology·2002
    Same author

    Peripheral eosinophilia in the diagnosis of chronic rhinosinusitis.

    American journal of otolaryngology·2001
    Same author

    The challenges and potential of otolaryngological telemedicine.

    Archives of otolaryngology--head & neck surgery·2001
    Same author

    Benchmarks for mortality, morbidity, and length of stay for head and neck surgical procedures.

    Archives of otolaryngology--head & neck surgery·2001
    Same author

    Assessment of the airway in obstructive sleep apnea syndrome with 3-dimensional airway computed tomography.

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2000
    Same journal

    Practice Patterns for the Management of Pediatric oSDB: What Is the Current National Landscape?

    The Laryngoscope·2026
    Same journal

    Vocal Fold Opening Position Impacts Bowing Measures in Age-Related Vocal Atrophy.

    The Laryngoscope·2026
    Same journal

    Association Between the Modified Frailty Index and Short-Term Total Thyroidectomy Complications.

    The Laryngoscope·2026
    Same journal

    Discrimination of Pairs of Chemosensory Stimuli in Relation to Respiration.

    The Laryngoscope·2026
    Same journal

    What Safety Precautions Are Recommended When Lasering in the Airway?

    The Laryngoscope·2026
    Same journal

    Success of Anterior Ethmoidal Artery Flaps for Nasal Septal Perforation Repair: A Systematic Review.

    The Laryngoscope·2026
    See all related articles

    Area of Science:

    • Otolaryngology
    • Pathology
    • Pharmacology

    Background:

    • Cervical adenopathy of unknown origin poses diagnostic challenges for otolaryngologists.
    • Hydantoin anticonvulsants are a rare cause of cervical adenopathy, presenting a spectrum from lymphoid hyperplasia to true lymphoma.

    Observation:

    • A patient on diphenylhydantoin (Dilantin) therapy developed bilateral true vocal cord paralysis and cervical adenopathy.
    • Initial pathological examination suggested malignant lymphoma, later reclassified as hydantoin-induced pseudolymphoma.

    Findings:

    • Hydantoin-induced adenopathy can clinically range from benign to malignant lymphoma.
    • The malignant form may manifest years after discontinuing anticonvulsant treatment.

    Implications:

    Related Experiment Videos

    • Epileptic patients on hydantoin therapy show a 10-fold increased incidence of malignant lymphoma, necessitating long-term monitoring.
    • Otolaryngologists must recognize hydantoin-induced pseudolymphoma as a potential cause of cervical adenopathy and vocal cord paralysis.