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Updated: Aug 15, 2026

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
Published on: August 19, 2013
[Fisher discriminant analysis for carcinogenic potency of aromatic amines]
Objective:
To study the relationship between carcinogenicity and their structure and physicochemical parameters of aromatic amines.
Methods:
Fisher discriminant analysis for carcinogenicity of aromatic amines in two different batches was conducted with estimation of parameters of physicochemical using central atom and functional groups in combination with structural parameters of polycyclic aromatic hydrocarbons (PAHs).
Results:
The discriminant efficacy approximated to that of the two in a series of equations (I and III) established by Yuta, but inferior to the optimal equation II.
Conclusion:
The selected physicochemical parameters can be applied to QSAR study on carcinogenicity of most aromatic amines, with better results in Fisher discriminant analysis.
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