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Published on: April 28, 2014
[Predictive factors of efficacy in antimicrobial prophylaxis for acute recurrent otitis media]
M P Prim Espada1, J I De Diego Sastre, C Alfonso Carrillo
1Servicio de Otorrinolaringología, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Spain.
Insights
Children with recurrent acute otitis media (AOM) who experienced their first AOM episode earlier and had a family history of AOM responded best to prophylactic antibiotics. These prognostic factors are key for effective AOM management.
Area of Science:
- Pediatric Otolaryngology
- Infectious Diseases
- Epidemiology
Context:
- Recurrent acute otitis media (AOM) poses a significant challenge in pediatric care.
- Prophylactic antibiotic treatment is a common strategy for managing recurrent AOM.
- Identifying prognostic factors can optimize treatment outcomes.
Purpose:
- To identify key prognostic factors influencing treatment success in children with recurrent AOM.
- To evaluate the impact of various patient and environmental variables on the response to prophylactic antibiotics.
Summary:
- A prospective study analyzed 69 children with recurrent AOM receiving prophylactic antibiotics.
- Favorable treatment response was significantly associated with an earlier age at the first AOM episode (p=0.004) and a positive family history of AOM (p=0.047).
- Other assessed variables did not show significant correlation with treatment outcomes.
Impact:
- Early age of first AOM episode and family history are crucial indicators for successful prophylactic treatment in recurrent AOM.
- Findings can guide clinicians in tailoring AOM management strategies.
- Highlights the importance of considering familial predisposition and early disease onset in pediatric otitis media.
Objective:
A prospective study was designed to assess the most relevant prognostic factors influencing outcome in children treated with antibiotics for recurrent acute otitis media (AOM).
Materials And Methods:
A prospective study was performed in 69 patients with recurrent AOM who received prophylactic treatment in the Pediatric Otorhinolaryngology Section of our hospital between January 1998 and May 1999. In all patients, 17 variables were registered: age, sex, family history of recurrent AOM, history of prematurity, history of allergies, use of day care centers, household smokers, maternal smoking, coincidence with dental eruption, symptoms of upper respiratory obstruction (snoring, breathing through the mouth, obstructive tonsils), episodes of tonsillitis per year, age at first AOM episode, season in which prophylaxis was started, and characteristics of neonatal feeding (breast or bottle feeding and position). ResultsThe mean age was 35.3 months (range: 9-120 months). There were 38 boys (55.1 %) and 31 girls (44.9 %). The factors related to a more favorable response to treatment were lower age at the first AOM episode (p 0.004) and a positive family history of AOM (p 0.047).
Conclusions:
The children that benefitted most from the prophylactic schedules for recurrent AOM were those that had the first episode at an earlier age and who had a positive family history of the disease.
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