Related Experiment Videos
Lepirudin anticoagulation for heparin-induced thrombocytopenia
Steven R Deitcher1, Arthur P Topoulos, John R Bartholomew
1Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA.
The Journal of Pediatrics
|February 28, 2002
Abstract:
Lepirudin is indicated for anticoagulation in patients with heparin-induced thrombocytopenia (HIT). We describe 2 cases of HIT and thrombosis in children with heart disease, including one that required extracorporeal membrane oxygenation. Lepirudin, dosed in the recommended adult weight--based fashion, was an effective antithrombotic agent in pediatric patients with HIT.