Related Experiment Video
Updated: Aug 18, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
[Group B streptococcal infection with 2 recurrences in a newborn]
M Lalande1, H Marchandin, L Enaud
1Service de pédiatrie III, centre hospitalier universitaire de Montpellier, hôpital Arnaud-de-Villeneuve, 34295 Montpellier, France.
Unlabelled:
Group B III streptococcus (GBS) is a predominant pathogen in neonates in France. Relapse is rare and two successive relapses are exceptional: only three cases have been yet reported.
Case Report:
A newborn infant of 18 days of age presented a first episode of invasive group B III streptococcal infection with meningitis and ventriculitis. At 53 days of age, a second episode with bacteriemia and parotidis appeared. At 63 days of age, she presented a third episode with meningitis. Genome analysis of the three bacterial strains isolated during the three episodes showed the same clonal origin.
Comments:
We discuss the incidence of the treatment, the eventual presence of a penicillin-tolerant GBS, the possible relapse or recurrence of the pathogen and the role of the relative immunodeficiency in infant.
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