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Anti-androgens for the treatment of hirsutism
1Department of Clinical Medicine, University of Palermo, via delle Croci 47, 90139 Palermo, Italy. enricocarmina@libero.it
Expert Opinion on Investigational Drugs
|February 28, 2002
Abstract:
Many alternatives exist for treating hirsutism. Based on an analysis of scientific literature and on the experiences of the author, the most common anti-androgen agents are discussed in this review. Androgen receptor blockers (cyproterone acetate, flutamide and spironolactone), 5 alpha-reductase inhibitors (finasteride) and androgen-suppressing agents (gonadotrophin-releasing hormone [GnRH] agonists, oestroprogestins, corticosteroids and insulin-sensitising agents) are evaluated and compared. The importance of diagnosis in choosing the most appropriate anti-androgen treatment is also discussed.