Related Experiment Videos
[Study on the needle biopsies of 100 prostatic adenocarcinoma]
1Department of Pathology, Shanghai Sixth People's Hospital, Shanghai 200233, China.
Objective:
To study the morphological diagnostic criteria of prostatic adenocarcinoma in needle biopsy.
Methods:
250 cases of prostatic needle biopsy including 100 cases of adenocarcinoma were observed retrospectively. The diagnostic significance of 20 parameters of morphological criteria including the architectural changes, cytologic features, invasion and some additional histologic features (intraepithelial neoplasm, intraluminal crystelloid body, intraluminal basophilic mucin secretion, collagen nodule and coagulative necrosis) were analyzed.
Results:
All 20 parameters of morphological criteria had practical significance in pathologic diagnosis, the most significant ones being architectural changes, prominent nucleoli, perineural and stromal invasion.
Conclusion:
The diagnosis of prostatic adenocarcinoma is based on a constellation of cytologic and architectural features.