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Assessing fluoride concentration uniformity and fluoride release from three varnishes
Chiayi Shen1, Jaana Autio-Gold
1University of Florida, College of Dentistry, Department of Dental Biomaterials, Gainesville 32610-0446, USA. cshen@dental.ufl.edu
Journal of the American Dental Association (1939)
|March 1, 2002
Summary
Fluoride varnish content uniformity varies significantly between brands, impacting fluoride release. Clinicians should note potential ingredient separation in some varnishes, affecting fluoride delivery.
Area of Science:
- Dental materials science
- Oral health product analysis
Background:
- Commercial fluoride varnishes are widely used for caries prevention.
- Understanding fluoride content uniformity and release is crucial for effective dental treatments.
Purpose of the Study:
- To compare the fluoride content uniformity and fluoride release characteristics of three commercial fluoride varnishes.
- To assess the impact of varnish formulation on fluoride delivery.
Main Methods:
- Evaluated fluoride content and release from Duraphat, Duraflor, and CavityShield varnishes.
- Used chloroform and distilled water for fluoride extraction.
- Measured fluoride concentrations using a fluoride-selective ion electrode.
Main Results:
- Statistically significant differences in fluoride content and release were observed between varnish groups.
- Duraphat and CavityShield exhibited more uniform fluoride content compared to Duraflor.
- Duraflor released a higher percentage of fluoride in artificial saliva than the other two varnishes.
Conclusions:
- Fluoride content can be non-uniform within doses from the same fluoride varnish tube.
- Variations in varnish uniformity affect fluoride retention and release.
- Clinicians should be aware of potential ingredient separation in fluoride varnishes, which can alter fluoride content.