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Ancient schwannoma masquerading as a thyroid mass
1Department of Endocrine Surgery, King's College Hospital, London, UK.
Summary
This study reports a rare ancient schwannoma of the cervical sympathetic chain (CSC) that mimicked a thyroid mass. It is the first such case documented, highlighting diagnostic challenges for parapharyngeal masses.
Area of Science:
- Oncology
- Neuropathology
- Endocrinology
Background:
- Schwannomas are benign nerve sheath neoplasms, with cervical sympathetic chain (CSC) schwannomas being exceptionally rare.
- Less than 50 cases of CSC schwannomas are documented, often presenting as parapharyngeal masses.
Observation:
- A rare variant, an ancient schwannoma of the CSC, was observed.
- This ancient schwannoma presented with both cytologic and radiologic features suggestive of a thyroid mass.
Findings:
- This case represents the first documented instance of a CSC schwannoma mimicking a thyroid mass.
- It is also the first report of an ancient schwannoma specifically arising from the CSC.
Implications:
- The findings underscore the importance of considering rare differentials in the diagnosis of parapharyngeal and neck masses.
- Accurate diagnosis is crucial, as ancient schwannomas can radiologically and cytologically resemble other thyroid and neck pathologies.