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[Observations on prostate histology in 50 young and middle aged men. Its implication on clinical pathological
Objective:
To investigate the morphology and the relationship between the prostate and the adjacent structures in order to clarify its significance in histopathological diagnosis.
Methods:
By means of light microscopy, and in part by electron microscopy and immunohistochemistry, the histology of 50 normal prostates were observed.
Results:
The parenchymal component can be divided into four zones, i.e. peripheral zone, central zone, transitional zone and periurethral gland region, each characterized by its own anatomical and histological features.
Conclusion:
This 4 zone division of prostate has more clinical significance than the traditional division of the prostate. A good knowledge of the normal structure of the prostate has great practical significance in pathologic diagnosis.