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[The amyloidosis in cardiac conduction system]
1Research Institute of Forensic Medicine, Medical College of Shantou University, Shantou 515031.
Objective:
To investigate the relationship between arrhythmia, cardiac failure and amyloidosis of cardiac conduction system (CCS).
Methods:
CCS from 6 cases with cardiac amyloidosis were sampled using technique designed by the authors. The CCS were studied by Congo red staining and polarization microscopy.
Results:
Pathological changes could be found in the CCS of these 6 cases. It was serious in sino-atrial node while slight in atrio-ventricular conduction system. The changes in atrio-ventricular conduction system were exacerbated from proximal part (atrio-ventricular node) to distal part (left bundle branch). In the 3 cases with sinus bradycardia and conduction blocking manifested by electrocardiogram, the pathological changes in CCS were more extensive and serious than that of other cases.
Conclusion:
The amyloidosis in CCS is one of the pathological bases of arrhythmia.