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Related Experiment Videos

Physical methods for preventing deep vein thrombosis in stroke.

C Mazzone1, F Chiodo Grandi, P Sandercock

  • 1U.C.O. Clinica Neurologica, University of Trieste, Ospedale di Cattinara, Trieste, Italy, 34100. fabio.chiodograndi@aots.sanita.fvg.it

The Cochrane Database of Systematic Reviews
|March 1, 2002
PubMed
Summary

Physical methods like compression stockings do not significantly prevent deep vein thrombosis (DVT) or pulmonary embolism (PE) in stroke patients. More research is needed to confirm their effectiveness and safety in this population.

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Area of Science:

  • Neurology
  • Vascular Medicine
  • Medical Interventions

Background:

  • Deep vein thrombosis (DVT) and pulmonary embolism (PE) are known complications following stroke.
  • Anticoagulants reduce DVT/PE risk but carry a bleeding risk.
  • Physical methods offer a bleeding-risk-free alternative for DVT/PE prevention in some patient groups.

Purpose of the Study:

  • To evaluate the efficacy of physical methods in preventing DVT and PE in recent stroke patients.
  • To assess the safety profile of these physical interventions in the stroke population.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs) and controlled clinical trials.
  • Searched multiple databases including Cochrane, MEDLINE, EMBASE, and CINAHL up to January 2001.

Related Experiment Videos

  • Included trials comparing physical methods initiated within one week of stroke onset against no physical methods.
  • Main Results:

    • Two small trials with 123 patients were identified.
    • Compression stockings showed a non-significant trend in reducing DVT.
    • Intermittent pneumatic compression did not significantly reduce DVT; overall physical methods showed no significant DVT or death reduction.

    Conclusions:

    • Current randomized trial evidence is insufficient to recommend routine physical methods for DVT prevention in acute stroke.
    • Further high-quality research is required to establish the role of physical methods in post-stroke DVT prophylaxis.