Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic eosinophilic perimyositis with persistent myalgias.

Sasa A Zivkovic1, David Lacomis, Paula R Clemens

  • 1Department of Neurology, University of Pittsburgh School of Medicine, BST South, Room S515, Pittsburgh, Pennsylvania 15213, USA.

Muscle & Nerve
|March 1, 2002
PubMed
Summary

Hypereosinophilia with persistent muscle pain may indicate eosinophilic perimyositis. Diagnosis requires muscle biopsy, especially when other tests are normal.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vamorolone for Duchenne Muscular Dystrophy: A Cross-Trial Efficacy Comparison With Classic Corticosteroids From the FOR-DMD Trial.

Neurology·2026
Same author

Case Report: Sustained immune and pulmonary recovery three years after hematopoietic stem cell transplantation for ITCH E3 ubiquitin ligase deficiency.

Frontiers in immunology·2026
Same author

Electrophysiology of Neuromuscular Disorders in Critical Illness.

Muscle & nerve·2026
Same author

What Is in the Myopathy Literature?

Journal of clinical neuromuscular disease·2026
Same author

Kinematic features of dysphagia in inclusion body myositis.

Neuromuscular disorders : NMD·2026
Same author

Adrenal Suppression in Duchenne Muscular Dystrophy: Management Strategies Incorporating Novel Steroid Vamorolone.

Journal of the Endocrine Society·2026

Area of Science:

  • Rheumatology
  • Neurology
  • Pathology

Background:

  • Persistent myalgia can be debilitating.
  • Hypereosinophilia is a condition characterized by elevated eosinophil counts.
  • Idiopathic hypereosinophilic syndromes can affect various organs.

Observation:

  • A 43-year-old male presented with an 8-year history of hypereosinophilia and persistent muscle pain.
  • Standard treatments like methotrexate and corticosteroids were ineffective.
  • Clinical examination revealed mild weakness, with pain limiting even passive motion.
  • Electromyography and muscle enzyme levels were within normal limits.

Findings:

  • Needle muscle biopsy confirmed eosinophilic perimyositis.
  • Histopathological evaluation is crucial for diagnosing this condition.

Related Experiment Videos

  • Eosinophilic perimyositis can present with normal electrodiagnostic and biochemical markers.

    • Implications:

    • This case highlights the importance of considering eosinophilic perimyositis in patients with unexplained myalgia and hypereosinophilia.
    • Muscle biopsy is essential for definitive diagnosis when standard tests are inconclusive.
    • Early diagnosis and targeted treatment can potentially improve patient outcomes and prevent further complications.