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Severe acute pancreatitis in acute hepatitis E
Satya Gopal Maity1, Gautam Ray
1Department of Gastroenterology, Institute of Postgraduate Medical Education and Research, S S K M Hospital, Kolkata. sgmaity@hotmail.com
Insights
A severe case of acute pancreatitis occurred in an 18-year-old male during hepatitis E infection. The patient recovered with supportive care for sepsis and acute renal failure complications.
Area of Science:
- Hepatology
- Gastroenterology
- Critical Care Medicine
Background:
- Hepatitis E virus (HEV) infection is a significant cause of acute hepatitis globally.
- Severe acute pancreatitis is a rare but serious complication of viral infections.
- Co-occurrence of hepatitis E and severe acute pancreatitis presents unique clinical challenges.
Observation:
- An 18-year-old male presented with symptoms of severe acute pancreatitis.
- The pancreatitis developed concurrently with acute hepatitis E infection.
- The patient subsequently developed sepsis and acute renal failure.
Findings:
- The case highlights a rare association between acute hepatitis E and severe acute pancreatitis.
- Supportive management was effective in treating the pancreatitis, sepsis, and renal failure.
- The patient achieved a full recovery.
Implications:
- This case underscores the potential for HEV to trigger severe extrapulmonary manifestations, including pancreatitis.
- Early recognition and aggressive supportive care are crucial for managing such complex cases.
- Further research may elucidate the pathogenic mechanisms linking HEV and acute pancreatitis.
Abstract:
We report an 18-year-old boy with severe acute pancreatitis developing during acute hepatitis E and complicated by sepsis and acute renal failure. The patient recovered on supportive management.