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Severe acute pancreatitis in acute hepatitis E.

Satya Gopal Maity1, Gautam Ray

  • 1Department of Gastroenterology, Institute of Postgraduate Medical Education and Research, S S K M Hospital, Kolkata. sgmaity@hotmail.com

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|March 2, 2002
PubMed
Summary

A severe case of acute pancreatitis occurred in an 18-year-old male during hepatitis E infection. The patient recovered with supportive care for sepsis and acute renal failure complications.

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Area of Science:

  • Hepatology
  • Gastroenterology
  • Critical Care Medicine

Background:

  • Hepatitis E virus (HEV) infection is a significant cause of acute hepatitis globally.
  • Severe acute pancreatitis is a rare but serious complication of viral infections.
  • Co-occurrence of hepatitis E and severe acute pancreatitis presents unique clinical challenges.

Observation:

  • An 18-year-old male presented with symptoms of severe acute pancreatitis.
  • The pancreatitis developed concurrently with acute hepatitis E infection.
  • The patient subsequently developed sepsis and acute renal failure.

Findings:

  • The case highlights a rare association between acute hepatitis E and severe acute pancreatitis.
  • Supportive management was effective in treating the pancreatitis, sepsis, and renal failure.

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  • The patient achieved a full recovery.

    • Implications:

    • This case underscores the potential for HEV to trigger severe extrapulmonary manifestations, including pancreatitis.
    • Early recognition and aggressive supportive care are crucial for managing such complex cases.
    • Further research may elucidate the pathogenic mechanisms linking HEV and acute pancreatitis.