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Updated: Oct 2, 2026

An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
Published on: March 30, 2018
Progressive intrathoracic lymphadenopathy: EBV associated non-Hodgkin's lymphoma
R F Miller1, E L Jones, M J Duddy
1Windeyer Institute of Medical Sciences, Royal Free and University College Medical School, University College London, UK.
Abstract:
A 30 year old man presented with late stage HIV disease and intrathoracic lymphadenopathy. Histology of a mediastinal biopsy suggested infective follicular hyperplasia or a peripheral T cell lymphoma. Subsequently, Epstein-Barr virus (EBV) infection was demonstrated in lymphocytes in the biopsy. Later, hepatosplenomegaly and peripheral lymphadenopathy developed. Histology of a cervical lymph node biopsy showed EBV associated diffuse large B cell (non-Hodgkin's) lymphoma.
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