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Related Experiment Videos

A study on Staphylococcus aureus strains submitted to a reference laboratory.

P L Mehndiratta1, S Vidhani, M D Mathur

  • 1National Staphylococcal Phage Typing Center, Department of Microbiology, Maulana Azad Medical College, New Delhi, India.

The Indian Journal of Medical Research
|March 5, 2002
PubMed
Summary
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Methicillin-resistant Staphylococcus aureus (MRSA) is spreading rapidly in India, with phage group III strains being most common. Increased MRSA occurrence necessitates ongoing surveillance for control.

Area of Science:

  • Microbiology
  • Epidemiology
  • Infectious Diseases

Background:

  • Staphylococcus aureus is a significant human pathogen.
  • Increasing incidence of methicillin-resistant Staphylococcus aureus (MRSA) strains reported globally.
  • Surveillance of MRSA and phage typing is crucial for understanding epidemiology.

Purpose of the Study:

  • To determine the prevalence of MRSA in India.
  • To identify the distribution of different phage groups among Staphylococcus aureus isolates.
  • To compare phage group prevalence between MRSA and methicillin-sensitive S. aureus (MSSA).

Main Methods:

  • Analysis of 7574 Staphylococcus aureus strains from 1992-1998.
  • Testing for methicillin resistance and susceptibility to international basic set phages.

Related Experiment Videos

  • Comparison of phage group occurrence between MRSA and MSSA, analyzed by geographical origin and source.
  • Main Results:

    • Phage group III was dominant across India, found in 62.32% of MRSA and 33.95% of MSSA isolates.
    • Highest isolation of phage group III from nasal carriers (45.94%).
    • MRSA occurrence increased from 9.83% in 1992 to 45.44% in 1998.

    Conclusions:

    • Phage group III Staphylococcus aureus strains are highly prevalent in India.
    • The alarming rise in MRSA indicates a widespread dissemination.
    • Continuous monitoring is essential for timely control measures against MRSA spread.