Toxicity of dietary lead in Japanese quail

The toxicity of dietary lead in Japanese quail was investigated. The data indicated that dietary lead, in the form of lead acetate, was toxic to young quail at the level of 500 p.p.m. and this toxicity was evidenced by an inhibition of normal growth and by anemia. The anemic state in the lead toxic quail was more readily detected by reduced blood hemoglobin concentrations than by packed cell volumes. In addition, the data suggested that lead interfered with normal sexual development in the males. Lead at levels as high as 1000 p.p.m. did not prevent normal primary antibody responses to sheep erythrocytes.