Nuclear organization and silencing: putting things in their place

HPL-2/HP1 and MET-2/SETDB1 bind distinct co-factors that promote heterochromatic foci, gene repression and organogenesis independently of H3K9 methylation.

bioRxiv : the preprint server for biology·2026

The Double Face of Base Excision Repair: Preventing and Triggering Double-Strand Breaks.

BioEssays : news and reviews in molecular, cellular and developmental biology·2025

Loss of cytoplasmic actin filaments raises nuclear actin levels to drive INO80C-dependent chromosome fragmentation.

Nature communications·2024

TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events.

Nature communications·2024

Chromatin remodeling and spatial concerns in DNA double-strand break repair.

Current opinion in cell biology·2024

SUMO in the regulation of DNA repair and transcription at nuclear pores.

FEBS letters·2023

An EZH2-SREBP2 axis promotes cholesterol biosynthesis and represents a noncanonical vulnerability in tumorigenesis.

Nature cell biology·2026

Targeting oncogenic FLT3 uncovers a ferroptosis vulnerability through selenocysteine recoding in acute myeloid leukaemia.

Nature cell biology·2026

Advanced imaging of membrane contact sites.

Nature cell biology·2026

Mega-enhancers compartmentalize transcriptionally active long genes in the brain.

Nature cell biology·2026

The mitochondria enzyme OGDH defends against disulfidptosis by licensing METTL3-regulated NRF2 translation.

Nature cell biology·2026

Stromal cell senescence augments haematopoietic cell fitness in clonal haematopoiesis.

Nature cell biology·2026

Rationally Designed Zwitterionic Peptides Improve siRNA Delivery of Cationic Diblock Copolymer-Based Nanoparticle Drug-Delivery Systems.

ACS applied nano materials·2026

In Vitro Evaluation of Silica-Coated Bi2Se3 Nanoplatelets as Photothermal Nanomaterials.

ACS omega·2026

Antiviral activity of biogenic silver nanoparticles against HSV-1: integrating computational modeling and experimental validation.

Iranian journal of microbiology·2026

Numerical study of the optimization of theranostic performance of (Au/SiO₂/Au) spherical gold nanomatryoshkas for cervical cancer through structural tuning: Comparative analysis in healthy and infected tissues.

Nanomedicine : nanotechnology, biology, and medicine·2026

Lithocholic based stimuli-responsive polymer capped silver nanoparticles: Assessment on bio interface driven colloidal stability, antimicrobial activity and ROS-mediated oral cancer therapy.

Colloids and surfaces. B, Biointerfaces·2026

ETfinder: harnessing conserved C-terminal tails of single-stranded DNA-binding proteins for mining and engineering RecET systems in non-model microbial chassis.

Nucleic acids research·2026

Related Experiment Videos

Nuclear organization and silencing: putting things in their place

Related Concept Videos

HPL-2/HP1 and MET-2/SETDB1 bind distinct co-factors that promote heterochromatic foci, gene repression and organogenesis independently of H3K9 methylation.

The Double Face of Base Excision Repair: Preventing and Triggering Double-Strand Breaks.

Loss of cytoplasmic actin filaments raises nuclear actin levels to drive INO80C-dependent chromosome fragmentation.

TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events.

Chromatin remodeling and spatial concerns in DNA double-strand break repair.

SUMO in the regulation of DNA repair and transcription at nuclear pores.

An EZH2-SREBP2 axis promotes cholesterol biosynthesis and represents a noncanonical vulnerability in tumorigenesis.

Targeting oncogenic FLT3 uncovers a ferroptosis vulnerability through selenocysteine recoding in acute myeloid leukaemia.

Advanced imaging of membrane contact sites.

Mega-enhancers compartmentalize transcriptionally active long genes in the brain.

The mitochondria enzyme OGDH defends against disulfidptosis by licensing METTL3-regulated NRF2 translation.

Stromal cell senescence augments haematopoietic cell fitness in clonal haematopoiesis.

Rationally Designed Zwitterionic Peptides Improve siRNA Delivery of Cationic Diblock Copolymer-Based Nanoparticle Drug-Delivery Systems.

In Vitro Evaluation of Silica-Coated Bi2Se3 Nanoplatelets as Photothermal Nanomaterials.

Antiviral activity of biogenic silver nanoparticles against HSV-1: integrating computational modeling and experimental validation.

Numerical study of the optimization of theranostic performance of (Au/SiO₂/Au) spherical gold nanomatryoshkas for cervical cancer through structural tuning: Comparative analysis in healthy and infected tissues.

Lithocholic based stimuli-responsive polymer capped silver nanoparticles: Assessment on bio interface driven colloidal stability, antimicrobial activity and ROS-mediated oral cancer therapy.

ETfinder: harnessing conserved C-terminal tails of single-stranded DNA-binding proteins for mining and engineering RecET systems in non-model microbial chassis.

Related Experiment Videos

Nuclear organization and silencing: putting things in their place

Related Concept Videos

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