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Updated: Oct 2, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
Published on: December 18, 2010
[Essence and significance of DIC-syndrome in acute peritonitis]
Abstract:
Section specimens of 20 patients who had died of peritonitis of different genesis and specimens of various organs from 10 rats which had of died experimental peritonitis were studied morphologically. It was revealed that 100% patients demonstrated intravascular blood coagulation, it was disseminated in 60% cases and localized--in 40%. In experimental peritonitis intravascular blood coagulation developed in 6 of 10 animals only, and it was disseminated in 3 rats only. It is demonstrated that microthrombi don't lead to focal necrosis due to their special localization in microcirculatory bed vessels.
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