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Updated: Aug 7, 2026
09:58
Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation
Published on: June 5, 2012
Summary
Mediastinal echinococcosis, a rare parasitic infection, was identified in 59 cases during autopsies. Surgical removal (echinococcectomy) with intraoperative prophylaxis is the primary treatment for this thoracic condition.
Area of Science:
- Parasitology
- Thoracic Surgery
- Immunology
Context:
- Mediastinal echinococcosis is a rare parasitic infection of the chest.
- The study analyzed autopsy and patient data to determine prevalence.
- 59 cases were found in 29,875 autopsies, and 55 in 4,178 thoracic echinococcosis patients.
Purpose:
- To report the incidence and surgical management of mediastinal echinococcosis.
- To evaluate the effectiveness of intraoperative prophylaxis.
- To assess the immunological changes post-surgery.
Summary:
- Surgical echinococcectomy was performed on all patients, with most undergoing ideal removal.
- Intraoperative prophylaxis involved treating the pleural cavity with low-frequency ultrasound and glycerin.
- Immunological studies in 7 patients showed reduced immune cell counts (CD3+, CD4+, CD8+, CD16+, CD21+) and increased immunoglobulins (A, M, G) and immune complexes.
Impact:
- Highlights the importance of surgical intervention for mediastinal echinococcosis.
- Suggests potential immunological alterations following treatment.
- Provides data on prophylaxis methods and their impact on immune markers.
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