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[Modified oligonucleotides containing 1-beta-D-galactopyranosylthymine: synthesis and substrate properties]
B S Ermolinskiĭ1, M V Fomicheva, E V Efimtseva
1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, Moscow, 117984 Russia.
Bioorganicheskaia Khimiia
|March 6, 2002
Abstract:
A convenient method of regioselective introduction of 1-beta-D-galactopyranosylthymine into oligonucleotides was developed and the substrate properties of the modified oligonucleotides were investigated in the enzymic reaction of formation and hydrolysis of internucleotide bonds. The English version of the paper.