Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Changes in hemogram parameters in infections].

P Kaminsky1, J Deibener, J F Lesesve

  • 1Unité d'accueil, hôpitaux de Brabois, CHU de Nancy, rue du Morvan, 54500 Vandoeuvre, France. p.kaminsky@chu-nancy.fr

La Revue De Medecine Interne
|March 6, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum to: Glomerular filtration rate estimated by Cockcroft-Gault formula better predicts anti-Xa levels than Modification of the diet in renal disease equation in older patients with prophylactic enoxaparin.

The journal of nutrition, health & aging·2024
Same author

Neutrophilic thrombophagocytosis.

Morphologie : bulletin de l'Association des anatomistes·2019
Same author

[Diagnostic journey of type 1 Gaucher Disease patients: A survey including internists and hematologists].

La Revue de medecine interne·2019
Same author

[Extensive digital necrosis during dermatomyositis associated with MDA-5 antibodies].

Annales de dermatologie et de venereologie·2016
Same author

Multiple acyl-CoA dehydrogenase deficiency (MADD) as a cause of late-onset treatable metabolic disease.

Revue neurologique·2016
Same author

Interference of blast cell fragments with automated platelet counting.

International journal of laboratory hematology·2015
Same journal

[Abdominal pain, fever and arthralgia in a 49-year-old woman].

La Revue de medecine interne·2026
Same journal

[Cardiorespiratory functional disorders: A transnosologic approach].

La Revue de medecine interne·2026
Same journal

[Diagnostic evaluation for suspected polycythemia].

La Revue de medecine interne·2026
Same journal

Heart involvements in systemic sclerosis beyond pulmonary hypertension: From conduction, rhythm and function defects to coronary artery disease.

La Revue de medecine interne·2026
Same journal

[Acute intermittent porphyria: When diagnostic errance jeopardizes patient health].

La Revue de medecine interne·2026
Same journal

Autosomal dominant polycystic kidney disease: Current perspectives in 2026.

La Revue de medecine interne·2026
See all related articles

Leukocytosis alone is a poor indicator of infection. Eosinopenia and lymphopenia are better predictors, but a detailed white blood cell count analysis is needed to reliably exclude infection.

Area of Science:

  • Clinical pathology
  • Infectious disease diagnostics
  • Hematology

Background:

  • Leukocytosis, an elevated white blood cell count, is often used as an indicator of infection.
  • However, its diagnostic accuracy for infection can be limited.

Purpose of the Study:

  • To compare the diagnostic value of leukocytosis with other white blood cell count parameters for predicting infection in patients with abdominal pain.
  • To evaluate the sensitivity and specificity of leukocytosis, eosinopenia, and lymphopenia in identifying infectious diseases.

Main Methods:

  • Analysis of white blood cell counts from 187 emergency room patients with abdominal pain, compared to healthy controls.
  • Patients were categorized into infectious (angiocholitis, cholecystitis, pyelonephritis) and non-infectious (biliary and nephritic colic) subgroups.

Related Experiment Videos

Main Results:

  • Leukocytosis and neutrophilia were observed in all patients compared to controls, with greater increases in infected patients.
  • Lymphopenia was significant in infectious diseases, while eosinopenia was significant in all patients.
  • Leukocytosis had 66% sensitivity and 56% specificity for infection; eosinopenia had 91% sensitivity and 38% specificity; lymphopenia had 58% sensitivity and 73% specificity.

Conclusions:

  • Leukocytosis, eosinopenia, and lymphopenia are individually poor indicators of infection.
  • Eosinopenia and lymphopenia show better predictive value for infection than leukocytosis.
  • A comprehensive analysis of the complete white blood cell differential count is crucial for accurately excluding infection.