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[Peripheral corneal edema after cataract extraction].

B Sun¹, Y He, P Zhong

¹Henan Institute of Ophthalmology, Zhengzhou, 450003.

[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology

|March 6, 2002

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Brown-Mclean syndrome is a rare peripheral corneal edema occurring years after cataract extraction. This condition affects the corneal periphery, sparing the center, and is linked to endothelial cell changes.

Area of Science:

Ophthalmology
Corneal Diseases
Postoperative Complications

Context:

Cataract extraction is a common surgical procedure.
Corneal edema is a known complication, but specific patterns can be rare.
Understanding rare syndromes aids in diagnosis and management.

Purpose:

To describe the clinical characteristics of a rare peripheral corneal edema post-cataract extraction, identified as Brown-Mclean syndrome.
To analyze the clinical presentation, pachymetry, and endothelial cell morphology in affected patients.
To discuss potential pathogenetic factors for this syndrome.

Summary:

A retrospective review of 8 eyes in 5 patients with Brown-Mclean syndrome was conducted.
The syndrome presented as peripheral corneal edema, typically starting inferiorly and progressing circumferentially, with a clear central cornea.

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Findings included increased corneal thickness in edematous areas, decreased endothelial cell density, and punctate orange-brown endothelial pigmentation, with diagnosis occurring an average of 10.5 years post-surgery.

Impact:

This report highlights a previously uncharacterized corneal edema syndrome in China.
The distinct clinical features differentiate Brown-Mclean syndrome from conventional post-cataract extraction edema.
Further research into the pathogenesis, potentially involving aphakia, chronic uveitis, or hereditary factors, is warranted.