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Determination of carbon monoxide in blood by means of microdiffusion
1University Medical School of Silesia, Faculty of Pharmacy, Department of General and Analytical Chemistry, Jagiellońska 4, Sosnowiec, Poland.
Abstract:
There was developed a little-work-consuming and non-expensive microdiffusion method of carboxyhaemoglobin determination in blood, in low range concentration. It can be used in the assessment of passive smokers' exposure to carbon monoxide. The amount of blood necessary for the determination was 0.15 ml. An average precision of the developed method of the carbon monoxide determination (converting into HbCO) for the concentration ranged from 1 to 5%, from 3 to 12% and from 5 to 20% was respectively 5.96, 4.09 and 2.14.
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