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Updated: Aug 12, 2026

Dissection and Immunohistochemistry of Larval, Pupal and Adult Drosophila Retinas
Published on: November 14, 2012
Photoreceptor cells in flies and mammals: Crumby homology?
Andrew P Kowalczyk1, Kevin Moses
1Department of Dermatology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Abstract:
Recently, two papers have revealed a new function for the fruit fly epithelial apical membrane protein Crumbs and its mammalian homolog CRB1 in photoreceptor cell morphogenesis. This supports the previous observation that disruption of CRB1 function can cause retinal degeneration in humans.
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